BONE MARROW Transplant
Bone marrow is an necessary organ of the hematopoietic system and malfunctions in its work ca serious dysfunction of blood cells. When, for some reason, the internal environment of the body - the blood - doesn't cope with its mission, bone marrow transplantation (BMT) is necessary - the patient' bone marrow is replaced with a healthy bone marrow.
Most frequently patients with diseases such as leukemia, various forms of lymphomas, myelomas, and anemias necessity bone marrow replacement. Hematology specialists several types of bone marrow transplants in Belarus:
- Autologous BMT - own blood stem cells of patient are transplanted to him.
- Allogenic transplantation a related donor - donor material a relative person is used.
- Allogenic transplantation an unrelated donor - stem cells are taken a compatible donor who's not a relative.
The choice of the type of transplantation depends on many factors: the effectiveness of conservative treatment, the age of the patient, and concomitant diseases. Also level of urgency of surgery is taken into account.
Photo Chad McNeeley
Thorough diagnostics of the recipient and the donor (if a donor transplant is required) to exclude the presence of infections in the body;
Collection and preparation of the graft (donor or autologous); the method of processing the biomaterial depends on the diagnosis and a number of other factors;
High-dose chemotherapy to destroy abnormal bone marrow cells (usually takes 5-6 days) - conditioning regimen;
Bone marrow transplantation;
Isolation and postoperative observation - in order to avoid the development of infections and other postoperative complications, at the end of the procedure, the patient is transferred to a special ward with a laminar air flow, where he remains until the bone marrow engraftment;
Outpatient follow-up, during which blood tests and other necessary studies are regularly performed to assess graft engraftment, monitor the underlying disease.
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